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The role of real-world evidence in health technology assessment decision-making: factors influencing integration and their implications for reimbursement decisions: a systematic literature review
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| 1.61 MB | Adobe PDF |
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Resumo(s)
This Systematic Literature Review (SLR) investigates the integration of Real-World Evidence
(RWE) into Health Technology Assessment (HTA) processes to address the limitations of
Randomized Controlled Trials (RCTs) in healthcare decision-making. The review examines
methodological, data quality, and regulatory factors influencing RWE adoption. Findings highlight
variations in HTA frameworks, barriers such as data interoperability challenges, and the potential
of RWE to complement traditional evidence. By synthesising evidence, this research underscores
RWE’s potential to complement traditional evidence, improve patient access, and inform
reimbursement decisions, supporting global efforts to optimise HTA methodologies and promote
equitable healthcare policies.
Descrição
Palavras-chave
Health technology assessment HTA Real-world evidence RWE Decision-making Reimbursement RWE Integration Healthcare systems