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Utility of virus genes inhibiting the interferon response

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Resumo(s)

"The African Swine Fever Virus (ASFV) is a large double-stranded DNA virus that replicates primarily in macrophages in vivo and endothelial cells in vitro. It causes a persistent infection in its natural host, the warthog, but a fulminant disease in domestic pig. Thus, it is a source of major economic losses in many African countries and a threat to pig farming worldwide. No vaccine currently exists, and therefore options for disease control are limited to destruction of infected pigs.(...)."

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virus vaccines African Swine Fever Virus Interferon, Viral evasion mechanisms I329L Toll-like Receptors

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Instituto de Tecnologia Química e Biológica António Xavier. Universidade NOVA de Lisboa.

Licença CC