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The role of real-world evidence in health technology assessment decision-making: best practices and lessons from successful RWE implementation - a systematic literature review

2025-01-06Dissertação de mestrado Acesso aberto
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datacite.subject.fosCiências Sociais::Economia e Gestãopt_PT
dc.contributor.advisorBarros, Pedro Pita
dc.contributor.advisorLeite, João
dc.contributor.authorMüller, Tizian Julius
dc.date.accessioned2025-03-28T18:02:53Z
dc.date.available2025-03-28T18:02:53Z
dc.date.issued2025-01-06
dc.date.submitted2024-12-17
dc.description.abstractThis Systematic Literature Review (SLR) investigates the integration of Real-World Evidence (RWE) into Health Technology Assessment (HTA) processes to address the limitations of Randomized Controlled Trials (RCTs) in healthcare decision-making. The SLR examines methodological, data quality, and regulatory factors influencing RWE adoption across diverse healthcare systems. The findings reveal significant variability in HTA practices across countries, highlighting barriers such as inconsistent frameworks and limited interoperability. By synthesising evidence, this research underscores RWE’s potential to complement traditional evidence, improve patient access, and inform reimbursement decisions, supporting global efforts to optimise HTA methodologies and promote equitable healthcare policies.pt_PT
dc.identifier.tid203927370pt_PT
dc.identifier.urihttp://hdl.handle.net/10362/181621
dc.language.isoengpt_PT
dc.relationUID/ECO/00124/2013pt_PT
dc.subjectReal-World Evidencept_PT
dc.subjectRWEpt_PT
dc.subjectHealth Technology Assessmentpt_PT
dc.subjectHTApt_PT
dc.subjectRandomized controlled trialspt_PT
dc.subjectRCTspt_PT
dc.subjectRWE Integrationpt_PT
dc.subjectDecision-makingpt_PT
dc.subjectReimbursementpt_PT
dc.subjectReimbursement decisionpt_PT
dc.subjectPolicy recommendationspt_PT
dc.subjectBest practicespt_PT
dc.subjectCase studiespt_PT
dc.subjectGuidelinespt_PT
dc.subjectFrameworkspt_PT
dc.subjectStandardspt_PT
dc.subjectInternational health systemspt_PT
dc.subjectHealthcare systemspt_PT
dc.subjectMethodological challengespt_PT
dc.subjectEvidence-Based Decision-Makingpt_PT
dc.titleThe role of real-world evidence in health technology assessment decision-making: best practices and lessons from successful RWE implementation - a systematic literature reviewpt_PT
dc.typemaster thesis
dspace.entity.typePublication
rcaap.rightsopenAccesspt_PT
rcaap.typemasterThesispt_PT
thesis.degree.nameA Work Project presented as part of the requirements for the Award of a Master’s degree in International Development and Public Policy from the Nova School of Business and Economicspt_PT

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Coleções

NSBE - MA Dissertations
NSBE: Health Economics & Management Knowledge Center