ITQB: SV- MA Dissertations
URI permanente para esta coleção:
Navegar
Entradas recentes
- The role of Ubiquitin Specific Protease 7 on Latency Associated Nuclear Antigen DNA bindingPublication . Nunes, Gonçalo Pedro da SilvaThe implications of USP7 (Ubiquitin Specific Protease 7, deubiquitinating enzyme involved in several crucial molecular pathways) interactions with LANA (Latency Associated Nuclear Antigen protein, that facilitates the tethering of viral γ-Herpesvirus episomes into the host’s DNA and promotes its replication) has multiple health consequences, since USP7 is a protein that has an essential role it the regulation of many cellular functions, like the p53-mdm2 pathway, that regulates cellular apoptosis and prevents cancer.