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Publicação
Unraveling phytochemicals with potential therapeutic application for neurodegeneration
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| 2.18 MB | Adobe PDF |
Autores
Orientador(es)
Resumo(s)
"Epidemiological data suggest that phytochemicals may prevent and even reverse specific pathological processes underlying neurodegenerative diseases. A (poly)phenol-enriched fraction from leaves of Corema album was previously reported to modulate central events related to α-Synuclein expression and aggregation as well as oxidative stress in eukaryotic models of Parkinson’s disease. In order to identify the potentially bioactive compound, this extract was subjected to a bioguided fractionation, leading to the identification of CAL_X.(...)"
Descrição
Palavras-chave
Parkinson´s disease Amytrophic lateral sclerosis Phytochemicals Yeast models
Contexto Educativo
Citação
Editora
Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier