A carregar...
Publicação
Pre-Clinical Evaluation of Targeted Therapies Using 3D Cell Models of Breast Cancer
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 45.3 MB | Adobe PDF |
Autores
Orientador(es)
Resumo(s)
"Breast cancer (BC) is the most frequent malignancy and the deadliest cancer death in women. It is a
heterogeneous disease characterized by high variability in tumor morphology, molecular characteristics, and
clinical response. Development of targeted therapies has revolutionized cancer treatment; however, these
therapies are associated with increased resistance. Development of novel therapies often fails due to lack of
representation of the tumor microenvironment (TME), revealing the need for recapitulative models.(...)"
Descrição
Palavras-chave
breast cancer targeted therapies; tumor microenvironment drug assays 3D cell models patient-derived explants
Contexto Educativo
Citação
Editora
Instituto de Tecnologia Química e Biológica António Xavier. Universidade NOVA de Lisboa.