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Investigating the role of nuclear packing in neuroepithelial development
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| 57.98 MB | Adobe PDF |
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Resumo(s)
"Pseudostratified epithelia (PSE) are critical for organogenesis across various species due
to their unique structure, where elongated cells with nuclei positioned at different levels
create dense nuclear stratification. This configuration is hypothesized to enhance cell
packing within a monolayered tissue, potentially aiding in precise organ development.
The current study aimed to investigate this hypothesis by employing advanced deep
learning techniques to achieve accurate 3D segmentation of nuclei in the zebrafish retina
during its development. (...)"
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Palavras-chave
pseudostratified epithelia nuclear packing 3D segmentation neurogenesis retina