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Publicação
Structure and function of designed and engineered proteins targeting SARS-CoV-2
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| 4.99 MB | Adobe PDF |
Orientador(es)
Resumo(s)
"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing COVID-2019 pandemic that, as of October 2022, has infected more than 600 million people all over the world, and caused more than 6 million deaths (1).
Coronaviruses (CoVs) are enveloped, single-stranded, positive-sense RNA viruses that form the Coronaviridae family. They are divided into four genera: alpha, beta, gamma, and delta. The beta genus is further divided into four lineages A, B, C, and D. SARS-CoV-2 belongs to the B lineage of Betacoronaviruses, along with SARS-CoV, which was responsible for an outbreak in 2002, human coronavirus (HCoV)-OC43, HCoV-HKU1 and Middle East respiratory syndrome coronavirus (MERS-CoV) which caused a serious outbreak in 2012 (2-5).(...)"
Descrição
Palavras-chave
SARS-CoV-2 multimeric protein display receptor binding domains antiviral proteins Protein binding
Contexto Educativo
Citação
Editora
Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa