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Biotechnological strategy for the exploitation of the invasive Asparagopsis armata as an underutilized natural source of bioactive compounds
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Resumo(s)
" Microorganism resistance to current antibiotics has increased morbidity and mortality, prompting the search for naturally occurring candidate drugs from terrestrial and marine sources. Algae can produce a wide range of bioactive secondary metabolites, some of which display biomedical potential in the treatment of human diseases. Multiple studies have shown that Asparagopsis spp. are promising sources of antimicrobial compounds. However, to date, the bioactivities of Asparagopsis aqueous extracts have never been tested against pathogenic fungi and bacteria. Additionally, this invasive species is present in several coastlines all over the world making it a sustainable, easily obtainable, natural resource. In this study, the capacity of various steam-based extraction methods to render bioactive extracts against the model microorganisms were thoroughly compared using metabolic activity (MTT) and viability (CFUs) assays.(...)"
Descrição
Palavras-chave
Marine resources Asparagopsis armata Steam distillation Antimicrobial activity
Contexto Educativo
Citação
Editora
Instituto de Tecnologia Química e Biológica António Xavier. Universidade Nova de Lisboa