Human lectins, their carbohydrate affinities and where to find them

Raposo, Cláudia D.; Canelas, André B.; Barros, M. Teresa

http://hdl.handle.net/10362/145941

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Autores

Raposo, Cláudia D.

Canelas, André B.

Barros, M. Teresa

Resumo(s)

Lectins are a class of proteins responsible for several biological roles such as cell-cell interactions, signaling pathways, and several innate immune responses against pathogens. Since lectins are able to bind to carbohydrates, they can be a viable target for targeted drug delivery systems. In fact, several lectins were approved by Food and Drug Administration for that purpose. Information about specific carbohydrate recognition by lectin receptors was gathered herein, plus the specific organs where those lectins can be found within the human body.

Descrição

POCI-01-0145-FEDER-007265

Palavras-chave

Biological applications Carbohydrate specific recognition Human lectins Protein expression Targeted drug delivery systems Biochemistry Molecular Biology