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Molecular modeling study of β-lactoglobulin dimerization: a first step to hypoallergen design for immunotherapy
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"Milk and its derivatives are important worldwide food sources, particularly for infant nutrition, but face a major health complication: some of their proteins are allergens, especially β-lactoglobulin (BLG), a major component of bovine milk.
The fate of BLG upon ingestion remains unsettled, being unclear how extensive BLG proteolysis is and how it affects allergenicity. The fact that proteolytic resistance and antigenic response remain related even for non-oral administration suggests that they are not causally related but rather reflect an underlying common feature.(...)"
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β-lactoglobulina alergénio dimerização comportamento sensível ao pH