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A possible case of acquired syphilis at the former Royal Hospital of All-Saints (RHAS) in Lisbon, Portugal (18th century)

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dc.contributor.authorAssis, Sandra
dc.contributor.authorCasimiro, Sílvia
dc.contributor.authorAlves Cardoso, Francisca
dc.contributor.institutionCentro em Rede de Investigação em Antropologia (CRIA - NOVA FCSH)
dc.contributor.pblSchweizerbart Science Publishers
dc.date.accessioned2018-01-19T23:05:04Z
dc.date.available2018-01-19T23:05:04Z
dc.date.issued2015
dc.descriptionSFRH/BD/36739/2007 SFRH/BPD/43330/2008 UID/ANT/04038/2013
dc.description.abstractBetween the years of 1999 and 2001, during the excavation of the Praça da Figueira (Lisbon, Portugal), several human osteological remains from various chronological periods were discovered. Amongst them several skeletons are known to be related with the Hospital Real de Todos-os-Santos (Royal Hospital of All Saints - RHAS), which had an important role. The hospital history begun in 1492 and ended in 1755 largely as a consequence of the Lisbon earthquake. Of the skeletons exhumed, one in particular, the adult female Sk. 1310 showed significant pathological changes. The bone lesions characterized by new bone deposition, with a symmetric and disseminate pattern, were found in the upper limbs, distal end of femurs and in tibia and fibula diaphyses. A bowing deformity with "sabre shape" morphology was also observed in the tibiae. The most striking lesions, characterized by healed nodular cavitations and similar to those of caries sicca, were recorded on the frontal bone. Considering the value of a complete description, as well as the application of multiple lines of enquiry for a reliable differential diagnosis, three distinct techniques were applied and compared: visual examination, imagiology and histology. The results showed that the macroscopic analysis coupled with conventional X-ray analysis were fundamental to obtain a possible diagnosis of acquired syphilis. In contrast, the CT-scan and the histological analyses were less informative. The application of a new scoring system also supports a diagnosis of acquired syphilis. This case-study constitutes the first evidence of syphilis associated with the RHAS, supporting historical data on the pivotal role that this hospital had on the treatment of several conditions, namely, syphilis.en
dc.description.versionauthorsversion
dc.description.versionpublished
dc.format.extent23
dc.format.extent1207916
dc.identifier.doi10.1967/s002449910026
dc.identifier.issn0003-5548
dc.identifier.otherPURE: 1721772
dc.identifier.otherPURE UUID: 4cc825d4-0357-4352-9f10-e4a0bdb7e083
dc.identifier.otherScopus: 84988891058
dc.identifier.otherPubMed: 26244715
dc.identifier.otherWOS: 000366344300004
dc.identifier.otherORCID: /0000-0001-8386-2009/work/48324976
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=84988891058&partnerID=8YFLogxK
dc.identifier.urlhttps://www.scopus.com/pages/publications/84988891058
dc.language.isoeng
dc.peerreviewedyes
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F36739%2F2007/PT
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F43330%2F2008/PT
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147310/PT
dc.subjectPaleopathology
dc.subjectSyphilis
dc.subjectArchaeology
dc.subjectImagiologic and histologic techniques
dc.subject47 Royal Hospital of All Saints
dc.subjectGeneral Medicine
dc.subjectEcology, Evolution, Behavior and Systematics
dc.subjectAnthropology
dc.subjectAnimal Science and Zoology
dc.titleA possible case of acquired syphilis at the former Royal Hospital of All-Saints (RHAS) in Lisbon, Portugal (18th century)en
dc.title.subtitlea comparative methodological approach to differential diagnosisen
dc.typejournal article
degois.publication.firstPage427
degois.publication.issue4
degois.publication.lastPage449
degois.publication.titleAnthropologischer Anzeiger
degois.publication.volume72
dspace.entity.typePublication
oaire.awardNumberSFRH/BD/36739/2007
oaire.awardNumberSFRH/BPD/43330/2008
oaire.awardNumberUID/ANT/04038/2013
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F36739%2F2007/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F43330%2F2008/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876/UID%2FANT%2F04038%2F2013/PT
oaire.fundingStreamSFRH
oaire.fundingStreamSFRH
oaire.fundingStream5876
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccess
relation.isProjectOfPublication6a69f3af-c139-46f1-b294-3770464468ad
relation.isProjectOfPublication266a408e-38be-4cf3-ae32-800474d66de2
relation.isProjectOfPublication37c8222e-443c-4de2-a36e-b9c739e067ba
relation.isProjectOfPublication.latestForDiscovery6a69f3af-c139-46f1-b294-3770464468ad

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