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Sensory and motor representations in the inferior olive of larval zebrafish

datacite.subject.fosNeurosciencept_PT
dc.contributor.advisorOrger, Michael
dc.contributor.authorFélix, Rita
dc.date.accessioned2020-08-04T16:50:53Z
dc.date.available2022-06-30T00:30:55Z
dc.date.issued2020-06-25
dc.date.submitted2020-08-04
dc.description.abstract"The olivo-cerebellar system plays a pivotal role in sensorimotor con- trol and coordination in vertebrates. According to a classical theory of cerebellar cortex, the inferior olive (IO) provides Purkinje cells with error information which drives motor learning in the cerebellum. Even though this process has been extensively studied over the last five decades, it re- mains unclear whether the nature of IO signals is more sensory, motor or both. In this thesis we address the nature of sensory and motor rep- resentations in the IO of larval zebrafish and investigate their potential interactions and spatial organization. We presented a set of visual stimuli to larval zebrafish and recorded calcium activity in genetically identified IO neurons with a 2-photon microscope while simultaneously tracking the fishes’ eye and tail movements. We found that most IO responses were binocular, direction selective and spatially organized.(...)"pt_PT
dc.identifier.urihttp://hdl.handle.net/10362/101970
dc.language.isoengpt_PT
dc.relationLINKING ACTIVITY IN GENETICALLY DEFINED NEURONS TO VISUOMOTOR ADAPTATION IN ZEBRAFISH CEREBELLUM
dc.subjectolivo-cerebellar systempt_PT
dc.subjectlarval zebrafishpt_PT
dc.titleSensory and motor representations in the inferior olive of larval zebrafishpt_PT
dc.typedoctoral thesis
dspace.entity.typePublication
oaire.awardNumberSFRH/BD/90105/2012
oaire.awardTitleLINKING ACTIVITY IN GENETICALLY DEFINED NEURONS TO VISUOMOTOR ADAPTATION IN ZEBRAFISH CEREBELLUM
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F90105%2F2012/PT
person.familyNameFélix
person.givenNameRita
person.identifier.ciencia-idBC1D-185D-7F93
person.identifier.orcid0000-0001-6186-1494
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctArtigos por publicarpt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typedoctoralThesispt_PT
relation.isAuthorOfPublication46008402-6303-4d71-8edf-398fd63078b8
relation.isAuthorOfPublication.latestForDiscovery46008402-6303-4d71-8edf-398fd63078b8
relation.isProjectOfPublication82c4a7f0-d337-43c5-91d3-8cb9442f600a
relation.isProjectOfPublication.latestForDiscovery82c4a7f0-d337-43c5-91d3-8cb9442f600a
thesis.degree.nameDissertation presented to obtain the Ph.D Degree in Neurosciencept_PT

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