Publicação
Nanostructuring silicon probes via electrodeposition: characterization of electrode coatings for acute in vivo neural recordings
| dc.contributor.advisor | Kampff, Adam | |
| dc.contributor.advisor | Fortunato, Elvira | |
| dc.contributor.author | Baião, Pedro de Abreu Avó | |
| dc.date.accessioned | 2015-04-09T16:36:11Z | |
| dc.date.available | 2015-04-09T16:36:11Z | |
| dc.date.issued | 2014-11 | |
| dc.date.submitted | 2015-04 | |
| dc.description.abstract | Understanding how the brain works will require tools capable of measuring neuron elec-trical activity at a network scale. However, considerable progress is still necessary to reliably increase the number of neurons that are recorded and identified simultaneously with existing mi-croelectrode arrays. This project aims to evaluate how different materials can modify the effi-ciency of signal transfer from the neural tissue to the electrode. Therefore, various coating materials (gold, PEDOT, tungsten oxide and carbon nano-tubes) are characterized in terms of their underlying electrochemical processes and recording ef-ficacy. Iridium electrodes (177-706 μm2) are coated using galvanostatic deposition under different charge densities. By performing electrochemical impedance spectroscopy in phosphate buffered saline it is determined that the impedance modulus at 1 kHz depends on the coating material and decreased up to a maximum of two orders of magnitude for PEDOT (from 1 MΩ to 25 kΩ). The electrodes are furthermore characterized by cyclic voltammetry showing that charge storage capacity is im-proved by one order of magnitude reaching a maximum of 84.1 mC/cm2 for the PEDOT: gold nanoparticles composite (38 times the capacity of the pristine). Neural recording of spontaneous activity within the cortex was performed in anesthetized rodents to evaluate electrode coating performance. | por |
| dc.identifier.uri | http://hdl.handle.net/10362/14666 | |
| dc.language.iso | eng | por |
| dc.subject | Neurons | por |
| dc.subject | Microelectrodes | por |
| dc.subject | Electrodeposition | por |
| dc.subject | Impedance | por |
| dc.subject | Cyclic voltammetry | por |
| dc.subject | Action potential | por |
| dc.title | Nanostructuring silicon probes via electrodeposition: characterization of electrode coatings for acute in vivo neural recordings | por |
| dc.type | master thesis | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | por |
| rcaap.type | masterThesis | por |
| thesis.degree.discipline | Engenharia de Micro e Nanotecnologias | por |
| thesis.degree.level | Grau de Mestre | por |
| thesis.degree.name | Dissertação | por |