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SuberSkin - plant defensive polymers in wound healing
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Autores
Orientador(es)
Resumo(s)
"A method for the extraction of suberin from cork using two different ionic liquids,
cholinium hexanoate and cholinium decanoate, was optimised through the use of a home-built
reactor. The use of stirring was essential to enhance the recovery yield of suberin. The
extraction of suberin with cholinium hexanoate was fully optimised, whereas that with
cholinium decanoate though promising needs further optimisation. Liquid state nuclear
magnetic resonance (NMR), gas phase chromatography coupled to mass spectrometry (GC-
MS), high pressure liquid chromatography (HPLC), differential scanning calorimetry (DSC),
dynamic light scattering (DLS) were used to characterize the extracted suberin. Limited
amounts of suberin samples extracted with cholinium decanoate were attained due to low
recovery yields. The most remarkable observation was attained using NMR which allowed us to
disclose the different configurations of acyl-glycerol ester bonds present in the extracted
polymer (i.e. its degree of cross linking). The obtained suberin was used to cast waterproof
films; this process was optimized.(...)"
Descrição
Palavras-chave
suberin keratinocytes wound-healing characterization cholinium decanoate cholinium hexanoate
Contexto Educativo
Citação
Editora
Universidade NOVA de LIsboa. Instituto de Tecnologia Química e Biológica António Xavier