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From diet to neuronal cells: Investigating the effects of circulating (poly)phenol metabolites on Parkinson's disease

datacite.subject.fosCiências Naturaispt_PT
dc.contributor.advisorSantos, Cláudia
dc.contributor.advisorPais, Teresa
dc.contributor.authorCarecho, Rafael
dc.date.accessioned2024-08-23T15:29:50Z
dc.date.embargo2027-03-31
dc.date.issued2024-06-20
dc.date.submitted2024-03-11
dc.description.abstract"Neurodegenerative diseases (NDs) are complex age-related disorders that are currently lacking a cure. Their rising number accounts for a tremendous societal burden that cannot be ignored. When most therapies fail to treat these diseases, prevention emerges as the most promising approach to manage the devastating consequences of NDs, such as Parkinson’s disease (PD). PD ranks among the most prevalent NDs, being a progressive movement disorder primarily affecting dopaminergic neurons in the brain. The failure of these networks triggers an increased state of neuroinflammation, oxidative stress and metabolic damage. (...)"pt_PT
dc.identifier.tid101781580pt_PT
dc.identifier.urihttp://hdl.handle.net/10362/170745
dc.language.isoengpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectNeurodegenerative diseases (NDs)pt_PT
dc.subjectPotential of dietary interventionspt_PT
dc.subject(poly)phenol-rich foodspt_PT
dc.subjectLMPWMspt_PT
dc.titleFrom diet to neuronal cells: Investigating the effects of circulating (poly)phenol metabolites on Parkinson's diseasept_PT
dc.title.alternativeNeuroprotection in Parkinson’s disease modelspt_PT
dc.typedoctoral thesis
dspace.entity.typePublication
oaire.awardNumberPD/BD/135492/2018
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/PD%2FBD%2F135492%2F2018/PT
oaire.fundingStreamOE
person.familyNameCarecho
person.givenNameRafael
person.identifier.orcid0000-0002-1638-8789
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.embargofctArtigos por publicarpt_PT
rcaap.rightsembargoedAccesspt_PT
rcaap.typedoctoralThesispt_PT
relation.isAuthorOfPublication2f3f4370-d363-43c5-a252-41c0defcc2be
relation.isAuthorOfPublication.latestForDiscovery2f3f4370-d363-43c5-a252-41c0defcc2be
relation.isProjectOfPublication7917d828-3083-4778-a3e7-2c59bf7ac42a
relation.isProjectOfPublication.latestForDiscovery7917d828-3083-4778-a3e7-2c59bf7ac42a
thesis.degree.nameDissertation presented to obtain the PhD degree in Molecular Biosciencespt_PT

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