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dc.contributor.authorGonçalves, José
dc.contributor.authorPequeno, João
dc.contributor.authorKrzisnik, Davor
dc.contributor.authorSobral, Paula
dc.contributor.authorAntunes, Joana
dc.contributor.institutionMARE - Centro de Ciências do Mar e do Ambiente
dc.contributor.institutionFaculdade de Ciências e Tecnologia (FCT)
dc.contributor.pblMDPI - Multidisciplinary Digital Publishing Institute
dc.date.accessioned2026-09-01T10:49:09Z
dc.date.available2026-09-01T10:49:09Z
dc.date.issued2026-06
dc.descriptionCopyright: © 2026 by the authors. Licensee MDPI, Basel, Switzerland.
dc.description.abstractNanoplastics (NPs, <100 nm) have emerged as nano-scale contaminants with superior mobility and biological barrier-crossing capacity, yet risk assessment fails due to unstandardized analytical methods and a lack of realistic exposure data. This perspective proposes an “Exposome–Microbiome–Immune” (EMI) framework as a One Health paradigm to integrate detection, toxicokinetics, and systemic effects. We prioritize the following actions: (i) validated nano–Fourier transform infrared spectroscopy (nanoFTIR) and surface-enhanced Raman spectroscopy (SERS) for environmental/human monitoring; (ii) multigenerational studies in zebrafish and organoids; (iii) longitudinal cohorts for biomonitoring. Without shifting from descriptive reviews to systems toxicology, NP risk will remain underestimated.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1143669
dc.identifier.doi10.3390/pollutants6020021
dc.identifier.issn2673-4672
dc.identifier.otherPURE: 172031655
dc.identifier.otherPURE UUID: 51eb1426-5d76-4ff6-bfb0-8cf6ab0f3d70
dc.identifier.otherScopus: 105043117342
dc.identifier.otherWOS: 001803711200001
dc.identifier.urihttp://hdl.handle.net/10362/205915
dc.identifier.urlhttps://www.scopus.com/pages/publications/105043117342
dc.language.isoeng
dc.peerreviewedyes
dc.subjectemergent contaminants
dc.subjecthuman health
dc.subjectnanoplastics
dc.subjectEnvironmental Science (miscellaneous)
dc.subjectEngineering (miscellaneous)
dc.subjectPharmacology, Toxicology and Pharmaceutics (miscellaneous)
dc.subjectSDG 3 - Good Health and Well-being
dc.titleNanoplasticsen
dc.title.subtitleAn Emerging Threat to Human Health—A Perspective Reviewen
dc.typejournal article
degois.publication.issue2
degois.publication.titlePollutants
degois.publication.volume6
dspace.entity.typePublication
rcaap.rightsopenAccess

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