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Synthesis and host recognition of Staphylococcus aureus peptidoglycan
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"Bacteria are able to establish relationships with other organisms, which may be temporary, as in a bacterial infection, or long-term, as in symbiosis. From the interplay between different organisms emerged the concept of “identity”, i.e. the need to distinguish “self” from “non-self”. Multicellular organisms have developed immune systems responsible for the detection of “non-self” organisms that lead to the activation of appropriate responses to maintain the organism in a state of homeostasis. In opposition, bacteria have developed mechanisms (virulence factors) to avoid their identification as harmful, in order to assure their survival within the host. (...)"
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S. aureus bacterial model