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Organismal homeostasis in sepsis

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"Optimal organismal function and survival in adverse conditions require robust homeostatic responses to challenging environmental conditions. Surviving a severe infection requires the synergy between resistance and disease tolerance, two evolutionarily conserved defense strategies that limit disease severity. Sepsis – a dysregulated host response to infection that leads to high risk of death – is a prime example of extreme homeostasis disruption and therefore constitutes an excellent model to study homeostasis and inter-organ communication principles.(...)"

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infection homeostasis sepsis antibiotics

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Licença CC