Cell cycle-based mechanism of epigenetic centromere propagation

Abstract

"The centromere is a chromosomal locus that is responsible for nucleating a structure called the kinetochore during mitosis. This structure serves as a binding platform for microtubules during mitosis, enabling segregation of genetic material to two daughter cells. Although fascinating, the function of the centromere was not the focus of my PhD work. Rather, it was the epigenetic nature of its propagation.(...)"