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Staphylococcus aureus: towards a comprehensive view on epidemiology and clonal spread
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| 4.63 MB | Adobe PDF |
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Resumo(s)
Staphylococcus aureus is known for its extraordinary capacity of colonizing
asymptomatically the anterior nares of humans. A high versatility allied to the
successive accumulation of resistance to almost all clinically available antibiotics,
made S. aureus a major human pathogen worldwide. Soon after the introduction of
methicillin into clinical practice, methicillin resistant S. aureus (MRSA) emerged as
a major pathogen in hospitals worldwide, and more recently in the community as
well. Methicillin susceptible S. aureus (MSSA) are also an important problem.
MSSA is responsible from mild to severe invasive infections, commonly due to
enhanced virulence content, rather than accumulation of resistance determinates.
However, many gaps in the knowledge of the epidemiology of MSSA remain to be
clarified.(...)
Descrição
Dissertation presented to obtain a PhD degree
in Biology/ Molecular Biology by the
Universidade Nova de Lisboa, Instituto de
Tecnologia Química e Biológica
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Contexto Educativo
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Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica