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Title: Staphylococcus aureus: towards a comprehensive view on epidemiology and clonal spread
Author: Conceição, Teresa
Advisor: de Lencastre, Hermínia
Aires de Sousa, Marta
Westh, Henrik
Defense Date: Mar-2011
Publisher: Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica
Abstract: Staphylococcus aureus is known for its extraordinary capacity of colonizing asymptomatically the anterior nares of humans. A high versatility allied to the successive accumulation of resistance to almost all clinically available antibiotics, made S. aureus a major human pathogen worldwide. Soon after the introduction of methicillin into clinical practice, methicillin resistant S. aureus (MRSA) emerged as a major pathogen in hospitals worldwide, and more recently in the community as well. Methicillin susceptible S. aureus (MSSA) are also an important problem. MSSA is responsible from mild to severe invasive infections, commonly due to enhanced virulence content, rather than accumulation of resistance determinates. However, many gaps in the knowledge of the epidemiology of MSSA remain to be clarified.(...)
Description: Dissertation presented to obtain a PhD degree in Biology/ Molecular Biology by the Universidade Nova de Lisboa, Instituto de Tecnologia Química e Biológica
Appears in Collections:ITQB: MG - PhD Theses

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