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|Title:||Metabolic and morphogenetic engineering of Bacillus subtilis: biotechnology for industry|
|Advisor:||Henriques, Adriano O.|
|Publisher:||Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica|
|Abstract:||The bacterium Bacillus subtilis plays a major role as model for Gram-positive research, and is widely used as industrial workhorse for the production of high-value enzymes and metabolites. Successful development of commercially-attractive strains and of original products is the key of innovation in microbial industry. Evolving a natural B. subtilis strain into an overproducer involves genetic engineering. In spite of a wide range of genetic tools and techniques available for B. subtilis, engineering of the metabolic pathways, with the purpose to reach industrially significant amount of products, requires a deep and specific understanding of the metabolism.(...)|
|Description:||Dissertation presented to obtain the Ph.D. degree in “Biology” at the Institute of Chemical and Biological Technology of the New University of Lisbon|
|Appears in Collections:||ITQB: MD - PhD Theses|
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