A carregar...
Publicação
Overcoming Central Nervous System-barriers by the development of hybrid structured systems for nose-to-brain drug delivery using clean technologies
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 7.51 MB | Adobe PDF |
Autores
Orientador(es)
Resumo(s)
The effective delivery of therapeutics into the brain is challenging since drugs or drug delivery systems (DDS) candidates are not able to cross the blood-brain barrier (BBB), making the development of new drugs alone not enough to ensure progresses in Central Nervous System (CNS) drug therapy. Due to several problems related with other routes of brain drug administration, the interest has increased towards exploring the possibility of intranasal administration. The nose-to-brain transport and the therapeutic viability of this route have been investigated for rapid and effective transport of drugs to CNS, but the development of nasal drug products for brain targeting is still faced with many challenges.(...)
Descrição
Palavras-chave
Central Nervous System Clean Technologies
Contexto Educativo
Citação
Editora
Universidade Nova de Lisboa, Instituto de Tecnologia Química e Biológica António Xavier