At the crossroad between innate immunity and RNA editing:

Kus, Krzysztof

http://hdl.handle.net/10362/56196

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Autores

Kus, Krzysztof

Orientador(es)

Athanasiadis, Alekos

Resumo(s)

Detection of foreign nucleic acids is a crucial component of innate immunity against viruses. For that purpose, cells are equipped with a repertoire of cytoplasmic and membrane-bound DNA/RNA sensors. Recognition of non-self nucleic acids leads to the activation of downstream pathways dedicated to elimination or containment of infection. One of the strategies to counteract viral infections is the production of interferons, the cytokines which alert neighboring cells about potential threats.(...)