A carregar...
Publicação
Neuronal circuits underlying learning of competing action strategies
| Nome: | Descrição: | Tamanho: | Formato: | |
|---|---|---|---|---|
| 10.26 MB | Adobe PDF |
Orientador(es)
Resumo(s)
The nervous system is an amazing adaptation that allows animals to react
to (and act on) their perception of the environment. One extremely
important feature of an organism is the capacity to learn new actions upon
exposure to new contexts, situations or necessities. When an action begins
to be learned, the behaviour is highly dependent on the expected value of
the outcome associated with it. However, with repetition, the execution of
an action can become less dependent on the value of its consequences,
and progress to a habit. Habitual behaviour is, in general, characterized by
the relative independence from the outcome, and seen instead as a
stimulus-response association. Several studies have pinpointed that these
two behavioural modes depend on dissociable circuits in the brain, with
dorsomedial striatum and basolateral amygdala involved in goal-directed
actions, and dorsolateral striatum involved in habits. Nevertheless, little is
known about their interaction during action learning, or how the system
balances both modes during the behaviour output. Furthermore,
dopamine, which is an important neuromodulator, has also been
associated with this process. Accordingly, dopamine depletion in
dorsolateral striatum leads to increased sensitivity to changes in the value
of the outcome.
Descrição
Palavras-chave
Biology Neuroscience