Please use this identifier to cite or link to this item: http://hdl.handle.net/10362/4203
Title: trans-Acting factors and cis elements involved in glucose repression of arabinan degradation in Bacillus subtilis.
Author: Sá-Nogueira, Isabel de
Inácio, José Manuel
Issue Date: Nov-2007
Publisher: American Society for Microbiology
Citation: Inácio J. M. and de Sá-Nogueira I. (2007) trans-acting factors and cis elements involved in glucose repression of arabinan degradation in Bacillus subtilis. Journal of Bacteriology 189(22): 8371-8376.
Abstract: In Bacillus subtilis, the synthesis of enzymes involved in the degradation of arabinose-containing polysaccharides is subject to carbon catabolite repression (CCR). Here we show that CcpA is the major regulator of repression of the arabinases genes in the presence of glucose. CcpA acts via binding to one cre each in the promoter regions of the abnA and xsa genes and to two cres in the araABDLMNPQ-abfA operon. The contributions of the coeffectors HPr and Crh to CCR differ according to growth phase. HPr dependency occurs during both exponential growth and the transitional phase, while Crh dependency is detected mainly at the transitional phase. Our results suggest that Crh synthesis may increase at the end of exponential growth and consequently contribute to this effect, together with other factors.
Description: Journal of Bacteriology (Nov 2007) 8371-8376
URI: http://hdl.handle.net/10362/4203
ISSN: 0021-9193 (Print)
1098-5530 (Online)
Appears in Collections:FCT: DCV - Artigos em revista internacional com arbitragem científica

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