Home collection (IHMT)
URI permanente para esta coleção:
Navegar
Entradas recentes
- Evidence of Crimean–Congo hemorrhagic fever virus in livestock and wildlife in Northeastern PortugalPublication . dos Santos, Fábio Abade; Duarte, Margarida D.; Caçote, António; Lourenço, António; Maroco, Diogo; Varela, Ana Rita; Bonifácio, Luís; Pimpão, Miguel; Henriques, Margarida; Duarte, Ana; Barros, Sílvia C.; Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM); Bioresources 4 Sustainability (GREEN-IT); Instituto de Tecnologia Química e Biológica António Xavier (ITQB); DCV - Departamento de Ciências da Vida; Nature Publishing GroupFollowing the death of an 83-year-old man from the district of Bragança, in north-eastern Portugal due to Crimean–Congo hemorrhagic fever (CCHF), a serological survey was conducted to investigate domestic and wild ruminants. The survey included samples from cattle(n = 94), sheep(n = 30), goats(n = 4), and red deer(n = 10) collected within the affected region and neighboring areas where the human case was reported. CCHF antibodies were detected by ELISA in the serum of sheep, cattle and red deer, corresponding to seropositivity rates of 3.33%, 38.29%, and 60%, respectively, indicating significant exposure to the virus. Indirect immunofluorescence assays further validated the ELISA results. Most of the positive cattle originate from farms located in the Guarda district, which are located close to the Spanish border. None of the goats was positive for CCHFV-antibodies and viral-RNA was not detected in any of the samples. CCHFV-RNA was also not detected in 15 ticks from Dermacentor and Rhipicephalus genera collected from vegetation or cattle, on one of the positive farms. Our findings suggest that CCHFV is actively circulating in northeastern Portugal. Reports of human cases of CCHF in Spain, particularly near the border with Portugal, are consistent with the detection of CCHFV-RNA in ticks feeding on domestic and wild animals in western Spain, highlighting the potential for cross-border transmission and suggesting an established circulation of CCHFV in the Iberian Peninsula.
- Analysis of the most common causes of blood donor deferral in Southern MozambiquePublication . Nhachigule, Carina; Matola, Odete; Munguambe, Abras; Nhangave, Amâncio; Caetano, Manuel; Loquiha, Osvaldo; Mabunda, Nédio; Instituto de Higiene e Medicina Tropical (IHMT); Springer VerlagBackground: Blood transfusion is essential in modern medicine, but transfusion of blood may present for both the blood donor as well as the recipient risks. Strategies such as pre-interview (including clinical assessment) of donors and the subsequent testing of donated blood for infectious agents are steps taken to guarantee blood transfusion safety. The information about the reasons for deferring blood donors is not only important for improving the availability of blood, but also for actions to improve the health of the population in general. This the study aimed to assess the frequency and reasons for blood donation deferrals at blood banks in southern Mozambique. Methods: This was a cross-sectional study conducted on blood donation candidates between December 2022 and January 2024 in the provinces of Gaza and Inhambane, situated in the southern region of Mozambique. Blood donation candidates answered a questionnaire on demographic characteristics and venous blood was collected in one 6 ml K2EDTA tube samples. The plasma was separated from the whole blood and used for serological and molecular tests for HIV, HBV and HCV. Deferral data in the routine pre-interview was subsequently collected at each blood bank. Results: A total of 3862 donors participated in the study, of which 72.2% were replacement donors. The overall donor deferral rate in pre-interview was 5.2%, with low hemoglobin being the main reason for temporary deferral at pre-interview (41.0%), followed by syphilis or other sexually transmitted infection suspect (23.0%). The HBV (50.8%) and HIV (30.5%) infections were the main reasons for permanent deferral. Male donors were less likely to be deferred for blood donation (AOR 0.63, 95% CI 0.45–0.89) compared to female donors. Conclusion: The method used to measure hemoglobin, the higher seroprevalence of infectious agents in donated blood, and the greater deferral of women may be related to the blood donors deferral protocol in Mozambique. This results reinforce the need to improve the process of clinical assessment, selection, and retention of blood donation candidates, to have consistent volunteer donors.
- Corrigendum to “Early weaning and anemia in children under 2 years old from indigenous peoples in Alagoas state, Brazil” [Hum. Nutr. Metab. 40 (2025) 200318] (Human Nutrition & Metabolism (2025) 40, (S2666149725000210), (10.1016/j.hnm.2025.200318))Publication . de Oliveira, Valéria Clarisse; Mosquera, Paola Soledad; dos Santos, Tamara Rodrigues; Ferreira, Haroldo S.; Lourenço, Bárbara H.; Cardoso, Marly A.; Laboratório Associado de Translacção e Inovação para a Saúde Global - LA Real (Pólo IHMT); Population health, policies and services (PPS); Global Health and Tropical Medicine (GHTM); Instituto de Higiene e Medicina Tropical (IHMT); Elsevier BVThe authors regret that the funding information in this article requires correction. In the “Funding” section, please replace the current text: In the “Funding” section, please replace the current text: "the Fundação para a Ciência e Tecnologia, Portugal (FCT; https://www.fct.pt/en/), institutional projects UID/04413/2020 and LA-REAL LA/P/0117/2020″ With: “This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001.” This correction is necessary because the original funding acknowledgment (FCT) does not apply to this work, and proper attribution to CAPES is required for compliance with funding regulations. The authors would like to apologise for any inconvenience caused.
- Collection of entomological, demographic, water and sanitation, and climatic data of interest for arbovirus surveillance in Praia, Cabo VerdePublication . Ferrero Gómez, Maria Lara; Fonseca Silva, Keily Lucienne; Pina, Bruno Dos Santos; Silva, Patrick; Lima da Cruz, Ulisses António; Lopes Fernandes, José Moniz; Ribeiro Rocha, Hélio Daniel; Instituto de Higiene e Medicina Tropical (IHMT); GigaScience PressVector-borne diseases, primarily those transmitted by mosquitoes, are a serious public health problem. Some, such as dengue, put half of the world’s population at risk. Combating these diseases requires multifaceted strategies, with vector surveillance and control playing key roles. Robust and predictive surveillance systems for vector-borne diseases, based on risk stratification, enable the implementation of appropriate interventions across time and space. Here, we present a collection of entomological, demographic, water and sanitation, and climatic data from Praia (Cabo Verde), a hotspot for mosquito-borne diseases. These data were collected from June to November 2022, at 40 sentinel points scattered across the urban area of Praia. They constitute a valuable source of information for developing predictive scenarios of arbovirus outbreak risk using statistical models applied to spatial and non-spatial indicators. These data demonstrate the utility of GBIF in transforming large volumes of occurrence data into valuable information for arbovirus surveillance and vector control.
- Early weaning and anemia in children under 2 years old from indigenous peoples in Alagoas state, BrazilPublication . de Oliveira, Valéria Clarisse; Mosquera, Paola Soledad; Santos, Tamara Rodrigues dos; Ferreira, Haroldo S.; Lourenço, Bárbara H.; Cardoso, Marly A.; Laboratório Associado de Translacção e Inovação para a Saúde Global - LA Real (Pólo IHMT); Population health, policies and services (PPS); Global Health and Tropical Medicine (GHTM); Instituto de Higiene e Medicina Tropical (IHMT); Elsevier BVObjectives: To investigate the frequency of breastfeeding (BF) practices and factors associated with early weaning and anemia in indigenous children under 2 years of age. Study design: A household cross-sectional study was conducted in 13 indigenous communities in Alagoas state, northeastern Brazil. Methods: Mothers of eligible children were interviewed to gather socioeconomic, demographic, health, and feeding practice data. Blood samples were collected to assess the hemoglobin concentration (Hb). Multiple Cox, linear, and Poisson regression models were employed to examine the factors associated with weaning and anemia (Hb < 110 g/L in children aged 6 months and older). Results: Of the 1303 households surveyed, 145 had children under 2 years old. The prevalence of exclusive BF at 6 months was only 19 %. High frequencies of anemia (42.5 %), bottle-feeding (70 %), and pacifier use (31 %) were observed. The use of bottle and pacifier was associated with early weaning. Bottle-feeding was significantly associated with anemia (PR = 2.62; 95 % CI: 1.42–4.84) after adjusting for household wealth index. Conclusions: BF practices among indigenous children do not meet WHO recommendations. The use of artificial nipples was linked to early weaning, and bottle feeding was associated with anemia after 6 months of age. These findings underscore the urgent need for interventions to promote, protect, and support BF in indigenous people, guiding multidisciplinary health teams in properly caring for young children in indigenous communities.
- Open Science Community Lisboa (OSC Lisboa)Publication . Riso, Brígida; Boavida, Clara; Marques, Cátia Teles e; Cisneiros, Miguel; Castro, Ricardo; Rehemtula, Salima; Faculdade de Ciências Sociais e Humanas (FCSH); Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM)
- Rede Internacional de Comunidades de Ciência Aberta locaisPublication . Boavida, Clara; Riso, Brígida; Almeida, Inês; Rehemtula, Salima; Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM)
- Diretrizes para a definição de uma política de partilha de dados de investigação de revistas científicasPublication . Boavida, Clara; Castro, Ricardo; Rehemtula, Salima; Faculdade de Ciências Sociais e Humanas (FCSH); Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM)
- As Comissões de ética em saúde e o acesso a dados de investigaçãoPublication . Conceição, Cláudia; Rehemtula, Salima; Laboratório Associado de Translacção e Inovação para a Saúde Global - LA Real (Pólo IHMT); Individual Health Care (IHC); Global Health and Tropical Medicine (GHTM); Instituto de Higiene e Medicina Tropical (IHMT)As Comissões de ética em saúde são obrigatórias por lei, nos estabelecimentos prestadores de cuidados de saúde desde 1995 e nas instituições de ensino superior e outros centros que desenvolvam investigação clínica desde 2018. Entre múltiplas atribuições, cabe-lhes “Avaliar, de forma independente, os aspetos metodológicos, éticos e legais dos estudos de investigação clínica que lhe são submetidos”, para além de “Assegurar o acompanhamento de todos os estudos de investigação clínica que decorrem na instituição desde o seu início até ao seu termo”. Neste poster apresentam-se essencialmente dois assuntos que colocam desafios à gestão de dados em investigação: 1 – Os compromissos assumidos com os participantes nos estudos. As pessoas que altruisticamente concordam em colaborar em projetos de investigação, na área da saúde, recebem, dos investigadores, informações que lhes permitem refletir se concordam em participar, sabendo o que é esperado delas e o que vai acontecer à informação que vão fornecer. O processo de participação é materializado num documento de “Informação ao participante” e de “Consentimento informado”. Neste documento são estabelecidos compromissos em que salientamos a confidencialidade e a gestão dos dados. A compatibilização de aspetos éticos e abundância de requisitos legais com diferentes interpretações, assim como a ausência de políticas institucionais de gestão de dados, são desafios. 2 – Acesso a registos clínicos para investigação A prática clínica gera diariamente um manancial de informação, recolhida com o fim de prestar cuidados de saúde, mas que tem potencial imenso de contribuir para a melhoria dessa prestação. As Comissões de ética apreciam projetos que utilizam registos clínicos para fins de investigação. Tem vindo a fazer-se um processo de reflexão em que se reconhece a necessidade deste tipo de investigação. A compatibilização de aspetos éticos e o direito à informação dos participantes com a interpretação diversa de requisitos legais são desafios.
- Softwares de gestão e publicação de dados de investigaçãoPublication . Vieira, André; Rocha, Dina; Borba, Filomena; Moura, Paula; Gonçalves, Rita; Rehemtula, Salima; Instituto de Higiene e Medicina Tropical (IHMT); Global Health and Tropical Medicine (GHTM)Tabela comparativa de características e funcionalidades de softwares para o depósito, gestão e publicação de dados de investigação disponíveis para instalação própria. Os softwares analisados são: Dataverse, InvenioRDM, CKAN, DSpace e uData. Os documentos partilhados estão abertos a contributos da comunidade. Assim, caso alguma informação precise de correção, atualização ou clarificação, poderão ser enviadas sugestões através do e-mail forumgdi-repositorios@fccn.pt ou da funcionalidade dos comentários nos seguintes ficheiros: - tabela resumo - tabela detalhada