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Temporal Control at Multiple Scales: Distinct Behavioral and Neural Signatures of When and How to Act

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INPDP_Sofia Freitas_24 October 2025.pdf44.2 MBAdobe PDF Ver/Abrir

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"The ability to act at the right time and with appropriate intensity is central to adaptive behavior. In this thesis, I investigate the mech- anisms underlying timing and vigor in action control, focusing on their independence and neural substrates. Using a Fixed Interval (FI) lever-pressing task, rats were trained to press a lever for water rewards delivered only after a predetermined interval had elapsed.(...)"

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Temporal control Dorsal medium striatum Photometry and Electrophysiology Fixed interval task Dopamine Timing and vigour

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Licença CC