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Resumo(s)
"Adaptive behavior requires animals to evaluate internal needs and
external demands, select appropriate actions, and execute them effectively.
These processes depend on the coordinated activity of
widely distributed brain systems. Among these, the cortex, basal
ganglia (BG), and cerebellum (CB) are central to motor control. Lesions
to each structure produce distinct impairments, suggesting they
function as partially dissociable modules within a hierarchically organized
yet parallel network. However, their specific contributions
to motor control remain incompletely understood. To directly assess
the relative roles of the BG and CB in behavioral control, we first
examined the effects of CB and BG ablations in mice performing multiple
variants of a water reach task.(...)"
Descrição
Palavras-chave
motor control discrete and continuous control behavior electrophysiology cerebellum cerebral cortex basal ganglia
