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Contributions of basal ganglia and cerebellum to discrete and continuous behavioral control

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PhDThesis_TeresaSD_2025.pdf101.18 MBAdobe PDF Ver/Abrir

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"Adaptive behavior requires animals to evaluate internal needs and external demands, select appropriate actions, and execute them effectively. These processes depend on the coordinated activity of widely distributed brain systems. Among these, the cortex, basal ganglia (BG), and cerebellum (CB) are central to motor control. Lesions to each structure produce distinct impairments, suggesting they function as partially dissociable modules within a hierarchically organized yet parallel network. However, their specific contributions to motor control remain incompletely understood. To directly assess the relative roles of the BG and CB in behavioral control, we first examined the effects of CB and BG ablations in mice performing multiple variants of a water reach task.(...)"

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motor control discrete and continuous control behavior electrophysiology cerebellum cerebral cortex basal ganglia

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Licença CC