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Structural and mechanistic studies of iron containing proteins
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Resumo(s)
Over the last few decades a large effort has been done in the structural biochemistry
field. This effort is based on the study of some proteins, namely metalloproteins, that
contain cofactors and/or active sites with metal ions in their constitution.
This thesis will focus on different studies performed in metalloproteins that contain
non-heme iron centers. An important point is their relation to oxygen and reactive oxygen species.
To perform these studies, fast kinetic techniques were used coupled to spectroscopic
techniques, such as Electronic Paramagnetic Resonance (EPR), Mössbauer and UVVisible.
Descrição
Dissertação apresentada para obtenção do Grau de Doutor em Bioquímica, ramo de Bioquímica-Física, pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia