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Publicação
Cyanine-based fluorescent probes for biomolecule detection and cell imaging
| Nome: | Descrição: | Tamanho: | Formato: | |
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| 4.98 MB | Adobe PDF |
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Orientador(es)
Resumo(s)
"To understand biological processes, it is crucial to explore
biomacromolecules and cellular structures in various conditions.
Fluorescence-based methods, particularly fluorescence microscopy, offer
simplicity, high sensitivity, and convenience in studying molecular events,
providing valuable insights into physiological and pathological processes.
However, the effectiveness of these techniques depends on the availability
of fluorescent probes with specific properties, such as low phototoxicity,
high biocompatibility, and a robust fluorescence response to changes in
their environment, such as the presence of biomolecules, alterations in
viscosity, or pH fluctuations. Many commercially available probes have
limitations, including fast photobleaching, high phototoxicity, and low
sensitivity. Thus, the search for new fluorescent probes that can address
these limitations and expand the range of available probes with diverse
emission wavelengths remains essential.(...)"
Descrição
Palavras-chave
cyanine dyes fluorescent probes fluorescence microscopy fluorescence spectroscopy