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Identification and characterization of bioactive secondary metabolites from the filamentous fungus Neurosporacrassa
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Resumo(s)
"The need for novel natural products arises from the continuous emergence of new pathogens and (multi)drug-resistant strains of known pathogens, as well as from the limited efficacy of existing treatment options in clinical practice. Fungi are major sources of natural products deriving from their secondary metabolism. These group of diverse disparate small molecules of fungal origin are usually not essential for growth, yet, they confer an advantage in the ecological niche.(...)"
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Palavras-chave
ionic liquids Aspergillus species Transcriptomic analysis cyclic peptid-base metabolites