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Endoplasmic Reticulum membranes are continuously required to maintain mitotic spindle size and forces
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"Dynamic spindle microtubules bind to, align, and move chromosomes to opposite sides of the cell, ensuring that each daughter cell gets precisely one copy of the genetic material at each division round. Mitosis has often been studied in the context of these isolated and alluring events, although changes in other intracellular compartments occur in parallel. In fact, membrane organelle function, localization, and proper partitioning upon cell division depend on interactions with the cytoskeleton. Whether, reciprocally, membrane organelles also impact the function of cytoskeletal elements remains less clear. Therefore, investigating the reorganization and interaction between several intracellular structures during mitosis may elucidate why and how such an incredibly efficient process takes place."
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mitotic chromosomes ER membrane