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The role of pneumococcal carbon metabolism in colonisation and invasive disease
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| 4.58 MB | Adobe PDF |
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Streptococcus pneumoniae is a common asymptomatic commensal of
the human nasopharynx. However, it is better known as a threatening
pathogen that causes serious diseases such as pneumonia, meningitis
and sepsis, as well as other less severe but more prevalent infections
(e.g. otitis media). With the increase of antibiotic resistance and the limited
efficacy of vaccines, pneumococcal infections remain a major problem.
Therefore, the discovery of new therapeutic targets and preventive drugs
are in high demand.(...)