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Metal-catalyzed cross-coupling reactions on azaindole synthesis and functionalization

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Resumo(s)

Azaindoles are rare in nature but extremely attractive for drug discovery programs. Azaindoles can be obtained by diverse methods, including those involving metal-catalyzed reactions. This important core has been fascinating the scientific community due to their challenging synthesis and relevant bioactivity. This paper highlights the diverse synthetic methodologies developed to date involving metal-catalyzed reaction to attain azaindoles and its functionalization.

Descrição

SFRH/BD/1428767/2018. POCI-01-0145-FEDER-007265.

Palavras-chave

Azaindole Cross-coupling reactions Heterocycles Metal-catalyzed Analytical Chemistry Chemistry (miscellaneous) Molecular Medicine Pharmaceutical Science Drug Discovery Physical and Theoretical Chemistry Organic Chemistry

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