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Exploring Monotopic quinone reductases
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Resumo(s)
"Respiratory chains are groups of membrane bound enzymes which
generate a membrane electrochemical potential by coupling an exergonic
reaction to the translocation of charges (electrons or ions, H+ or Na+) across the
membrane. Quinone reductases are considered the electron entry point of
respiratory chains as they connect the different catabolic pathways from the
soluble cytoplasmic reactions to the membrane bound respiratory chains.
Quinone reductases can be classified in transmembrane or monotopic (placed
at a single side of the lipid bilayer), with only the first ones directly contributing
to the generation of the membrane electrochemical potential. Currently, 20
different “electron donor”:quinone oxidoreductase enzymatic activities have
been described, from which 10 are monotopic.(...)"
Descrição
Palavras-chave
quinone Staphylococcus aureus