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Early events of cell autonomous response against Toxoplasma gondii in the mouse

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Ana Rodrigues_Final.pdf76.51 MBAdobe PDF Ver/Abrir

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"Toxoplasma gondii is a widely spread parasite worldwide among warmblooded organisms thanks to its ability to survive the immune system response and chronically establish itself in its hosts. The success of T. gondii depends entirely on the establishment of its intracellular survival niche, called the parasitophorous vacuole (PV). The PV membrane (PVM) is derived from the host plasma membrane at the point of entry. Both at time of entry and from within the vacuole, the parasites release virulence factors into the cytoplasm that restrict the immune response.(...)"

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Toxoplasma gondii parasite

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Licença CC