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Supercomplexes of Prokaryotic Aerobic Respiratory Chains-Escherichia coli and Bacillus subtilis supramolecular assemblies
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Aerobic respiratory chains are composed of a series of membrane complexes
that catalyze the electron transfer from reducing substrates to oxygen. The energy
released through this process is used to translocate protons across the
membranes, thus generating a proton motive force that activates F1FO-ATP
synthase to synthesize ATP. The arrangement of these enzymes in the inner
mitochondrial membrane is well characterized in mammalian mitochondria, where
different sets of supramolecular assemblies, or supercomplexes, involving the
majority of the respiratory complexes were described, reinforcing the idea of an
operational solid state model wherein the oxidative phosphorylation processes are
optimized.(...)
Descrição
Dissertation presented to obtain the Ph.D degree in Biochemistry.
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Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica.