Application of Dithiocarbamates as potential new antitrypanosomatids-drugs:

Johny Wysllas de Freitas, Oliveira,; Hugo Alexandre Oliveira, Rocha,; Wendy Marina Toscano Queiroz, de Medeiros,; Silva, MS

http://hdl.handle.net/10362/116732

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Autores

Johny Wysllas de Freitas, Oliveira,

Hugo Alexandre Oliveira, Rocha,

Wendy Marina Toscano Queiroz, de Medeiros,

Silva, MS

Resumo(s)

Dithiocarbamates represent a class of compounds that were evaluated in different biomedical applications because of their chemical versatility. For this reason, several pharmacological activities have already been attributed to these compounds, such as antiparasitic, antiviral, antifungal activities, among others. Therefore, compounds that are based on dithiocarbamates have been evaluated in different in vivo and in vitro models as potential new antimicrobials. Thus, the purpose of this review is to present the possibilities of using dithiocarbamate compounds as potential new antitrypanosomatids-drugs, which could be used for the pharmacological control of Chagas disease, leishmaniasis, and African trypanosomiasis.

Palavras-chave

African trypanosomiasis Chagas disease DETC Trypanosomatids Antiparasitic activity Dithiocarbamates Leishmaniasis SDG 3 - Good Health and Well-being

URI

http://hdl.handle.net/10362/116732

DOI

10.3390/molecules24152806

Coleções

IHMT: PM - Artigos em revista internacional com arbitragem científica

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