A computational method for the identification of dengue, zika and chikungunya virus species and genotypes

In recent years, an increasing number of outbreaks of Dengue, Chikungunya and Zika viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is crucial to understand the emergence and spread of outbreaks, both aspects that are vital to develop effective prevention and treatment strategies. Hence, we developed an efficient method to classify virus sequences with respect to their species and sub-species (i.e. serotype and/or genotype). This tool provides an easy-to-use software implementation of this new method and was validated on a large dataset assessing the classification performance with respect to whole-genome sequences and partial-genome sequences.

Palavras-chave

Computer Science Applications Virology Infectious Diseases Genetics SDG 3 - Good Health and Well-being

URI

http://hdl.handle.net/10362/116728

DOI

10.1371/journal.pntd.0007231

Coleções

IHMT: MM - Artigos em revista internacional com arbitragem científica

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