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Immunity-related GTPases (IRGs) in the house mouse and the parasite Toxoplasma gondii in South America
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Resumo(s)
"The Immunity-related GTPases (IRGs) are IFNγ-inducible genes essential
for resistance against intracellular pathogens in the house mouse. In some
wild-derived house mice, such as the Eurasian mice CIM strain, polymorphic
IRG genes have been linked to the control of virulent strains of the
intracellular parasite Toxoplasma gondii. The house mouse (Mus musculus
domesticus) arrived in the Americas on the first European vessels in the
16th century, but they had never encountered infections with the highly
virulent T. gondii strains present in South America.(...)"
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Palavras-chave
parasite mice Toxoplasma gondii South America