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The Role of Actin-Capping Protein and Src signalling in tissue growth and apoptosis during Drosophila wing development
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The actin cytoskeleton controls numerous cellular processes, including cell morphology
and polarity, endocytosis, intracellular trafficking, contractility and cell division. Actin
filament growth, stability and disassembly are controlled by a plethora of actin-binding
proteins. Among them Capping Protein is a highly conserved αβ heterodimer, which
binds the barbed ends of actin filaments, inhibiting addition or loss of actin monomers.(...)
Descrição
Dissertation presented to obtain the Ph.D degree in Developmental Biology
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Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica.