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http://hdl.handle.net/10362/102210| Title: | Improving γ-retrovirus and lentivirus gene therapy vectors |
| Other Titles: | From producer cell engineering to transduction performance |
| Author: | Oliveira, Ana |
| Advisor: | Coroadinha, Ana Sofia de Sousa Valente |
| Keywords: | gene therapy products biotechnological clinical applications vector design |
| Defense Date: | 2-Jul-2020 |
| Abstract: | "In the last decade gene therapy became an effective form of treatment for several disease indications. Successful clinical trials saved the lives of many patients otherwise with untreatable diseases and numerous products were granted market approval. Gammaretroviral and lentiviral vectors (γ- RV and LV) are the gene delivery vehicles with higher representation in clinical trials and commercialized virus-based products. (...)" |
| URI: | http://hdl.handle.net/10362/102210 |
| Designation: | Dissertation presented to obtain the Ph.D degree in Molecular Biosciences |
| Appears in Collections: | ITQB: CLDMB - PhD Theses |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Ana Oliveira_PhD thesis_v2.pdf | 6,03 MB | Adobe PDF | View/Open |
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