Logo do repositório
 
Publicação

Associations of changes in reported and estimated protein and energy intake with changes in insulin resistance, glycated hemoglobin, and BMI during the PREVIEW lifestyle intervention study

2021-11-08Artigo científico Acesso aberto
Ver registo simples
dc.contributor.authorDrummen, Mathijs
dc.contributor.authorAdam, Tanja C
dc.contributor.authorMacdonald, Ian A
dc.contributor.authorJalo, Elli
dc.contributor.authorLarssen, Thomas M
dc.contributor.authorMartinez, J Alfredo
dc.contributor.authorHandjiev-Darlenska, Teodora
dc.contributor.authorBrand-Miller, Jennie
dc.contributor.authorPoppitt, Sally D
dc.contributor.authorStratton, Gareth
dc.contributor.authorPietiläinen, Kirsi H
dc.contributor.authorTaylor, Moira A
dc.contributor.authorNavas-Carretero, Santiago
dc.contributor.authorHandjiev, Svetoslav
dc.contributor.authorMuirhead, Roslyn
dc.contributor.authorSilvestre, Marta P
dc.contributor.authorSwindell, Nils
dc.contributor.authorHuttunen-Lenz, Maija
dc.contributor.authorSchlicht, Wolfgang
dc.contributor.authorLam, Tony
dc.contributor.authorSundvall, Jouko
dc.contributor.authorRaman, Laura
dc.contributor.authorFeskens, Edith
dc.contributor.authorTremblay, Angelo
dc.contributor.authorRaben, Anne
dc.contributor.authorWesterterp-Plantenga, Margriet S
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblAmerican Society for Nutrition (ASN)
dc.date.accessioned2021-12-22T23:26:06Z
dc.date.available2021-12-22T23:26:06Z
dc.date.issued2021-11-08
dc.description© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition.
dc.description.abstractBACKGROUND: Observed associations of high-protein diets with changes in insulin resistance are inconclusive. OBJECTIVES: We aimed to assess associations of changes in both reported and estimated protein (PRep; PEst) and energy intake (EIRep; EIEst) with changes in HOMA-IR, glycated hemoglobin (HbA1c), and BMI (in kg/m2), in 1822 decreasing to 833 adults (week 156) with overweight and prediabetes, during the 3-y PREVIEW (PREVention of diabetes through lifestyle intervention and population studies In Europe and around the World) study on weight-loss maintenance. Eating behavior and measurement errors (MEs) of dietary intake were assessed. Thus, observational post hoc analyses were applied. METHODS: Associations of changes in EIEst, EIRep, PEst, and PRep with changes in HOMA-IR, HbA1c, and BMI were determined by linear mixed-model analysis in 2 arms [high-protein-low-glycemic-index (GI) diet and moderate-protein-moderate-GI diet] of the PREVIEW study. EIEst was derived from energy requirement: total energy expenditure = basal metabolic rate × physical activity level; PEst from urinary nitrogen, and urea. MEs were calculated as [(EIEst - EIRep)/EIEst] × 100% and [(PRep - PEst)/PEst] × 100%. Eating behavior was determined using the Three Factor Eating Questionnaire, examining cognitive dietary restraint, disinhibition, and hunger. RESULTS: Increases in PEst and PRep and decreases in EIEst and EIRep were associated with decreases in BMI, but not independently with decreases in HOMA-IR. Increases in PEst and PRep were associated with decreases in HbA1c. PRep and EIRep showed larger changes and stronger associations than PEst and EIEst. Mean ± SD MEs of EIRep and PRep were 38% ± 9% and 14% ± 4%, respectively; ME changes in EIRep and En% PRep were positively associated with changes in BMI and cognitive dietary restraint and inversely with disinhibition and hunger. CONCLUSIONS: During weight-loss maintenance in adults with prediabetes, increase in protein intake and decrease in energy intake were not associated with decrease in HOMA-IR beyond associations with decrease in BMI. Increases in PEst and PRep were associated with decrease in HbA1c.This trial was registered at clinicaltrials.gov as NCT01777893.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent12
dc.format.extent356949
dc.identifier.doi10.1093/ajcn/nqab247
dc.identifier.issn0002-9165
dc.identifier.otherPURE: 35480446
dc.identifier.otherPURE UUID: 56f7e170-5b12-42ab-94cc-8ac69f97faf9
dc.identifier.otherPubMed: 34375397
dc.identifier.otherPubMedCentral: PMC8574694
dc.identifier.otherORCID: /0000-0001-9327-2897/work/105210301
dc.identifier.otherScopus: 85122224960
dc.identifier.urihttp://hdl.handle.net/10362/129675
dc.language.isoeng
dc.peerreviewedyes
dc.subjectAdult
dc.subjectAged
dc.subjectBody Mass Index
dc.subjectDietary Proteins/administration & dosage
dc.subjectEnergy Intake
dc.subjectFemale
dc.subjectGlycated Hemoglobin A/analysis
dc.subjectHumans
dc.subjectInsulin Resistance
dc.subjectLife Style
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectSDG 3 - Good Health and Well-being
dc.titleAssociations of changes in reported and estimated protein and energy intake with changes in insulin resistance, glycated hemoglobin, and BMI during the PREVIEW lifestyle intervention studyen
dc.typejournal article
degois.publication.firstPage1847
degois.publication.issue5
degois.publication.lastPage1858
degois.publication.titleThe American journal of clinical nutrition
degois.publication.volume114
dspace.entity.typePublication
rcaap.rightsopenAccess

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
nqab247.pdf
Tamanho:
348.58 KB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

NMS - Artigos em revista internacional com arbitragem científica