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Gynocare update

2021-02Artigo científico Acesso aberto
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dc.contributor.authorDi Fiore, Riccardo
dc.contributor.authorSuleiman, Sherif
dc.contributor.authorEllul, Bridget
dc.contributor.authorO’toole, Sharon A.
dc.contributor.authorSavona-Ventura, Charles
dc.contributor.authorFelix, Ana
dc.contributor.authorFelix, Ana
dc.contributor.authorNapolioni, Valerio
dc.contributor.authorConlon, Neil T.
dc.contributor.authorErson-Bensan, Ayse Elif
dc.contributor.authorKahramanoglu, Ilker
dc.contributor.authorAzzopardi, Miriam J.
dc.contributor.authorDalmas, Miriam
dc.contributor.authorCalleja, Neville
dc.contributor.authorBrincat, Mark R.
dc.contributor.authorMuscat-Baron, Yves
dc.contributor.authorSabol, Maja
dc.contributor.authorDimitrievska, Vera
dc.contributor.authorYordanov, Angel
dc.contributor.authorVasileva-Slaveva, Mariela
dc.contributor.authorvon Brockdorff, Kristelle
dc.contributor.authorMicallef, Rachel A.
dc.contributor.authorKubelac, Paul
dc.contributor.authorAchimas-Cadariu, Patriciu
dc.contributor.authorVlad, Catalin
dc.contributor.authorTzortzatou, Olga
dc.contributor.authorPoka, Robert
dc.contributor.authorGiordano, Antonio
dc.contributor.authorFelice, Alex
dc.contributor.authorReed, Nicholas
dc.contributor.authorHerrington, C. Simon
dc.contributor.authorFaraggi, David
dc.contributor.authorCalleja-Agius, Jean
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblMDPI - Multidisciplinary Digital Publishing Institute
dc.date.accessioned2021-02-02T23:39:25Z
dc.date.available2021-02-02T23:39:25Z
dc.date.issued2021-02
dc.description.abstractMore than 50% of all gynecologic tumors can be classified as rare (defined as an incidence of ≤6 per 100,000 women) and usually have a poor prognosis owing to delayed diagnosis and treatment. In contrast to almost all other common solid tumors, the treatment of rare gynecologic tumors (RGT) is often based on retrospective studies, expert opinion, or extrapolation from other tumor sites with similar histology, leading to difficulty in developing guidelines for clinical practice. Currently, gynecologic cancer research, due to distinct scientific and technological challenges, is lagging behind. Moreover, the overall efforts for addressing these challenges are fragmented across different European countries and indeed, worldwide. The GYNOCARE, COST Action CA18117 (European Network for Gynecological Rare Cancer Research) programme aims to address these challenges by creating a unique network between key stakeholders covering distinct domains from concept to cure: basic research on RGT, biobanking, bridging with industry, and setting up the legal and regulatory requirements for international innovative clinical trials. On this basis, members of this COST Action, (Working Group 1, “Basic and Translational Research on Rare Gynecological Cancer”) have decided to focus their future efforts on the development of new approaches to improve the diagnosis and treatment of RGT. Here, we provide a brief overview of the current state-of-the-art and describe the goals of this COST Action and its future challenges with the aim to stimulate discussion and promote synergy across scientists engaged in the fight against this rare cancer worldwide.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent14
dc.format.extent681433
dc.identifier.doi10.3390/cancers13030493
dc.identifier.issn2072-6694
dc.identifier.otherPURE: 27834162
dc.identifier.otherPURE UUID: 43008d2b-a25d-44b7-a549-c9b6dd16274e
dc.identifier.otherScopus: 85099822577
dc.identifier.otherORCID: /0000-0002-2653-2262/work/87993704
dc.identifier.otherPubMed: 33514073
dc.identifier.otherWOS: 000615016300001
dc.identifier.urihttp://hdl.handle.net/10362/111177
dc.identifier.urlhttps://www.scopus.com/pages/publications/85099822577
dc.language.isoeng
dc.peerreviewedyes
dc.subjectBiobanking
dc.subjectCancer stem cells
dc.subjectCirculating tumor-specific markers
dc.subjectPersonalized medicine
dc.subjectRare gynecologic tumors
dc.subjectTheranostics
dc.subjectOncology
dc.subjectCancer Research
dc.subjectSDG 3 - Good Health and Well-being
dc.titleGynocare updateen
dc.title.subtitleModern strategies to improve diagnosis and treatment of rare gynecologic tumors—current challenges and future directionsen
dc.typejournal article
degois.publication.firstPage1
degois.publication.issue3
degois.publication.lastPage14
degois.publication.titleCancers
degois.publication.volume13
dspace.entity.typePublication
person.familyNameFelix
person.givenNameAna
person.identifier.ciencia-idA617-A56B-6FC6
person.identifier.orcid0000-0002-2653-2262
person.identifier.scopus-author-id55574221034
rcaap.rightsopenAccess
relation.isAuthorOfPublicatione267d7fd-7e65-4533-9f0a-6fceabcf4b7b
relation.isAuthorOfPublication.latestForDiscoverye267d7fd-7e65-4533-9f0a-6fceabcf4b7b

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