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Lower serum magnesium is associated with cardiovascular risk factors and mortality in haemodialysis patients

2014-05-22Artigo científico Acesso aberto
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dc.contributor.authorMatias, Patrícia João
dc.contributor.authorAzevedo, Ana
dc.contributor.authorLaranjinha, Ivo
dc.contributor.authorNavarro, David
dc.contributor.authorMendes, Marco
dc.contributor.authorFerreira, Carina
dc.contributor.authorAmaral, Tiago
dc.contributor.authorJorge, Cristina
dc.contributor.authorAires, Inês
dc.contributor.authorGil, Célia
dc.contributor.authorFerreira, Aníbal
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblS. Karger AG
dc.date.accessioned2024-01-31T23:44:21Z
dc.date.available2024-01-31T23:44:21Z
dc.date.issued2014-05-22
dc.descriptionPublisher Copyright: © 2015 S. Karger AG, Basel.
dc.description.abstractBackground: Hypomagnesaemia is a cardiovascular (CV) risk factor in the general population. The aim of this study was to evaluate the relationship between pre-dialysis magnesium (Mg) and CV risk markers, [including pulse pressure (PP), left ventricular mass index (LVMI) and vascular calcifications (VC)], and mortality in haemodialysis (HD) patients. Methods: We performed a 48-month prospective study in 206 patients under pre-dilution haemodiafiltration with a dialysate Mg concentration of 1 mmol/l. Results: Lower Mg concentrations were predictors of an increased PP (≥65 mm Hg) (p = 0.002) and LVMI (≥140 g/m2) (p = 0.03) and of a higher VC score (≥3) (p = 0.01). Patients with Mg <1.15 mmol/l had a lower survival at the end of the study (p = 0.01). Serum Mg <1.15 mmol/l was an independent predictor of all-cause (p = 0.01) and CV mortality (p = 0.02) when adjusted for multiple CV risk factors. Conclusions: Lower Mg levels seem to be associated with increased CV risk markers, like PP, LVMI and VC, and with higher mortality in HD patients.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent9
dc.format.extent1113220
dc.identifier.doi10.1159/000366124
dc.identifier.issn0253-5068
dc.identifier.otherPURE: 82600462
dc.identifier.otherPURE UUID: a54d463f-9eaf-4fbe-91b5-8edcf70cb8ba
dc.identifier.otherScopus: 84929654402
dc.identifier.otherPubMed: 25573320
dc.identifier.otherWOS: 000349638200014
dc.identifier.urihttp://hdl.handle.net/10362/162983
dc.identifier.urlhttps://www.scopus.com/pages/publications/84929654402
dc.language.isoeng
dc.peerreviewedyes
dc.subjectHaemodialysis
dc.subjectMagnesium
dc.subjectMortality
dc.subjectVascular calcifications
dc.subjectHematology
dc.subjectNephrology
dc.titleLower serum magnesium is associated with cardiovascular risk factors and mortality in haemodialysis patientsen
dc.typejournal article
degois.publication.firstPage244
degois.publication.issue3-4
degois.publication.lastPage252
degois.publication.titleBlood Purification
degois.publication.volume38
dspace.entity.typePublication
rcaap.rightsopenAccess

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