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Using procalcitonin to guide antimicrobial duration in sepsis
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Orientador(es)
Resumo(s)
Severe sepsis is a major healthcare problem and the early initiation of antimicrobials is one of the few measures associated with improved outcomes. However, antibiotic overuse is an increasing problem in critical care. Of several potential biomarkers for antibiotic stewardship, procalcitonin represents the most widely studied and validated. In this commentary we address the current literature on the use of biomarkers to guide antimicrobial therapy in the critically ill and discuss its limitations and future directions.
Descrição
Funding Information: PP has an unrestricted research grant from ThermoFisher Scientific and Virogates. The other authors state that they have no competing interests.
Palavras-chave
Critical Care and Intensive Care Medicine