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Portuguese recommendations for the use of methotrexate in rheumatic diseases - 2016 update

2017-05-24Artigo científico Desconhecido
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dc.contributor.authorDuarte, Ana Catarina
dc.contributor.authorSantos-Faria, Daniela
dc.contributor.authorGonçalves, Maria João
dc.contributor.authorSepriano, Alexandre
dc.contributor.authorSepriano, Alexandre
dc.contributor.authorMourão, Ana Filipa
dc.contributor.authorDuarte, Cátia
dc.contributor.authorNeves, Joana Sousa
dc.contributor.authorÁgueda, Ana Filipa
dc.contributor.authorRibeiro, Pedro Avila
dc.contributor.authorDaniel, Alexandra
dc.contributor.authorNeto, Adriano
dc.contributor.authorCordeiro, Ana
dc.contributor.authorRodrigues, Ana
dc.contributor.authorMaria Rodrigues, Ana
dc.contributor.authorBarcelos, Anabela
dc.contributor.authorSilva, Cândida
dc.contributor.authorPonte, Cristina
dc.contributor.authorVieira-Sousa, Elsa
dc.contributor.authorTeixeira, Filipa
dc.contributor.authorOliveira-Ramos, Filipa
dc.contributor.authorAraújo, Filipe
dc.contributor.authorBarcelos, Filipe
dc.contributor.authorCanhão, Helena
dc.contributor.authorCanhão, Helena
dc.contributor.authorSantos, Helena
dc.contributor.authorRamos, João
dc.contributor.authorPolido-Pereira, Joaquim
dc.contributor.authorTavares-Costa, José
dc.contributor.authorMelo Gomes, José António
dc.contributor.authorCunha-Miranda, Luís
dc.contributor.authorCosta, Lúcia
dc.contributor.authorCerqueira, Marcos
dc.contributor.authorCruz, Margarida
dc.contributor.authorSantos, Maria José
dc.contributor.authorBernardes, Miguel
dc.contributor.authorOliveira, Paula
dc.contributor.authorAbreu, Pedro
dc.contributor.authorFigueira, Ricardo
dc.contributor.authorBarros, Rita
dc.contributor.authorFalcão, Sandra
dc.contributor.authorPinto, Patrícia
dc.contributor.authorPimenta, Sofia
dc.contributor.authorCapela, Susana
dc.contributor.authorTeixeira, Vitor
dc.contributor.authorFonseca, João Eurico
dc.contributor.institutionCentro de Estudos de Doenças Crónicas (CEDOC)
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblSociedade Portuguesa de Reumatologia
dc.date.accessioned2018-03-15T23:19:01Z
dc.date.available2018-03-15T23:19:01Z
dc.date.issued2017-05-24
dc.description.abstractBACKGROUND: Methotrexate (MTX) is the first-line drug in the treatment of rheumatoid arthritis (RA) and the most commonly prescribed disease modifying anti-rheumatic drug. Moreover, it is also used as an adjuvant drug in patients under biologic therapies, enhancing the efficacy of biologic agents. OBJECTIVES: To review the literature and update the Portuguese recommendations for the use of MTX in rheumatic diseases first published in 2009. METHODS: The first Portuguese guidelines for the use of MTX in rheumatic diseases were published in 2009 and were integrated in the multinational 3E Initiative (Evidence Expertise Exchange) project. The Portuguese rheumatologists based on literature evidence and consensus opinion formulated 13 recommendations. At a national meeting, the recommendations included in this document were further discussed and updated. The document resulting from this meeting circulated to all Portuguese rheumatologists, who anonymously voted online on the level of agreement with the updated recommendations. RESULTS: Results presented in this article are mainly in accordance with previous guidelines, with some new information regarding hepatitis B infection during MTX treatment, pulmonary toxicity monitoring, hepatotoxicity management, association with hematologic neoplasms, combination therapy and tuberculosis screening during treatment. CONCLUSION: The present recommendations combine scientific evidence with expert opinion and attained desirable agreement among Portuguese rheumatologists. The regular update of these recommendations is essential in order to keep them a valid and useful tool in daily practice.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent14
dc.format.extent306880
dc.identifier.issn0303-464X
dc.identifier.otherPURE: 3695144
dc.identifier.otherPURE UUID: 72df6aac-4f48-47a7-9c72-343b95e0f062
dc.identifier.otherPubMed: 28535545
dc.identifier.otherWOS: 000405771400003
dc.identifier.otherScopus: 85054100649
dc.identifier.otherORCID: /0000-0003-1894-4870/work/67178311
dc.identifier.urihttp://www.actareumatologica.pt/archive_detail.php?id=214
dc.identifier.urlhttp://www.actareumatologica.pt/archive_detail.php?id=214
dc.language.isoeng
dc.peerreviewedyes
dc.subjectSDG 3 - Good Health and Well-being
dc.titlePortuguese recommendations for the use of methotrexate in rheumatic diseases - 2016 updateen
dc.typejournal article
degois.publication.firstPage127
degois.publication.issue2
degois.publication.lastPage140
degois.publication.titleActa Reumatológica Portuguesa
degois.publication.volume42
dspace.entity.typePublication
person.familyNameSepriano
person.familyNameRodrigues
person.familyNameCanhão
person.givenNameAlexandre
person.givenNameAna Maria
person.givenNameHelena
person.identifier397398
person.identifier405554
person.identifier379800
person.identifier.ciencia-id5E1B-9976-5CE4
person.identifier.ciencia-idAE18-DA10-460C
person.identifier.ciencia-id5A17-C6D9-DBC8
person.identifier.orcid0000-0003-1954-0229
person.identifier.orcid0000-0003-2046-8017
person.identifier.orcid0000-0003-1894-4870
person.identifier.ridC-9611-2018
person.identifier.scopus-author-id55266526300
person.identifier.scopus-author-id57189499663
person.identifier.scopus-author-id6602393492
rcaap.rightsopenAccess
relation.isAuthorOfPublicationd87df0c7-841b-4648-a99e-296348e2e286
relation.isAuthorOfPublicatione2b860b7-6a22-4bc8-a7ff-676ca22da61c
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relation.isAuthorOfPublication.latestForDiscoverye2b860b7-6a22-4bc8-a7ff-676ca22da61c

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