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The role of nutrition in the prevention and management of bronchopulmonary dysplasia

dc.contributor.authorRocha, Gustavo
dc.contributor.authorGuimarães, Hercília
dc.contributor.authorPereira-da-Silva, Luís
dc.contributor.authorPereira-da-Silva, Luís
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.institutionComprehensive Health Research Centre (CHRC) - pólo NMS
dc.contributor.pblMolecular Diversity Preservation International (MDPI)
dc.date.accessioned2021-07-05T22:18:18Z
dc.date.available2021-07-05T22:18:18Z
dc.date.issued2021-06-02
dc.description.abstractBronchopulmonary dysplasia (BPD) remains the most common severe complication of preterm birth, and nutrition plays a crucial role in lung growth and repair. A practical nutritional approach for infants at risk of BPD or with established BPD is provided based on a comprehensive literature review. Ideally, infants with BPD should receive a fluid intake of not more than 135‒150 mL/kg/day and an energy intake of 120‒150 kcal/kg/day. Providing high energy in low volume remains a challenge and is the main cause of growth restriction in these infants. They need a nutritional strategy that encompasses early aggressive parenteral nutrition and the initiation of concentrated feedings of energy and nutrients. The order of priority is fortified mother’s own milk, followed by fortified donor milk and preterm enriched formulas. Functional nutrient supplements with a potential protective role against BPD are revisited, despite the limited evidence of their efficacy. Specialized nutritional strategies may be necessary to overcome difficulties common in BPD infants, such as gastroesophageal reflux and poorly coordinated feeding. Planning nutrition support after discharge requires a multidisciplinary approach to deal with multiple potential problems. Regular monitoring based on anthropometry and biochemical markers is needed to guide the nutritional intervention.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent2405752
dc.identifier.doi10.3390/ijerph18126245
dc.identifier.issn1661-7827
dc.identifier.otherPURE: 32122154
dc.identifier.otherPURE UUID: e5086605-d274-4655-a5e1-f3f69752e778
dc.identifier.otherScopus: 85107449291
dc.identifier.otherWOS: 000666452400001
dc.identifier.otherPubMed: 34207732
dc.identifier.urihttp://hdl.handle.net/10362/120543
dc.identifier.urlhttps://www.scopus.com/pages/publications/85107449291
dc.language.isoeng
dc.peerreviewedyes
dc.subjectBronchopulmonary dysplasia
dc.subjectEnriched formulas
dc.subjectFluid restriction
dc.subjectGrowth monitoring
dc.subjectHuman milk fortification
dc.subjectPreterm infants
dc.subjectPollution
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectHealth, Toxicology and Mutagenesis
dc.subjectSDG 3 - Good Health and Well-being
dc.titleThe role of nutrition in the prevention and management of bronchopulmonary dysplasiaen
dc.title.subtitleA literature review and clinical approachen
dc.typereview
degois.publication.issue12
degois.publication.titleInternational Journal of Environmental Research and Public Health
degois.publication.volume18
dspace.entity.typePublication
person.familyNamePereira-da-Silva
person.givenNameLuís
person.identifier170920
person.identifier.ciencia-id001E-3D9B-A4CF
person.identifier.orcid0000-0002-6480-1048
person.identifier.ridA-3469-2008
rcaap.rightsopenAccess
relation.isAuthorOfPublication69bc8408-2804-4ca3-a938-90b72cadda88
relation.isAuthorOfPublication.latestForDiscovery69bc8408-2804-4ca3-a938-90b72cadda88

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