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Examining comorbidities in children with diarrhea across four provinces of Mozambique

2023-09Artigo científico Acesso aberto
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dc.contributor.authorBauhofer, Adilson Fernando Loforte
dc.contributor.authorSambo, Júlia
dc.contributor.authorChilaúle, Jorfélia J.
dc.contributor.authorConjo, Carolina
dc.contributor.authorMunlela, Benilde
dc.contributor.authorChissaque, Assucênio
dc.contributor.authorIsaías, Telma
dc.contributor.authorDjedje, Marlene
dc.contributor.authorde Deus, Nilsa
dc.contributor.institutionInstituto de Higiene e Medicina Tropical (IHMT)
dc.contributor.institutionGlobal Health and Tropical Medicine (GHTM)
dc.contributor.institutionPopulation health, policies and services (PPS)
dc.contributor.pblPLOS - Public Library of Science
dc.date.accessioned2024-03-12T00:15:45Z
dc.date.available2024-03-12T00:15:45Z
dc.date.issued2023-09
dc.descriptionPublisher Copyright: Copyright: © 2023 Bauhofer et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
dc.description.abstractComorbidities are defined as the simultaneous occurrence of two or more diseases within the same individual. Comorbidities can delay a patient’s recovery and increase the costs of treatment. Assessing comorbidities can provide local health care policy-makers with evidence of the most common multi-health impairments in children. This could aid in redirecting and integrating care and treatment services by increasing health facilities the awareness and readiness of health facilities. The present analysis aims to determine the frequency and associated factors of comorbidities in children with diarrhea in Mozambique. A cross-sectional hospital-based analysis was conducted between January 2015 and December 2019 in children up to 59 months of age who were admitted with diarrhea in six reference hospitals in Mozambique. These hospitals are distributed across the country’s three regions, with at least one hospital in each province from each region. Sociodemographic and clinical data were obtained through semi-structured interviews and by reviewing the child clinical process. Descriptive statistics, and Mann-Whitney-U tests were used. Crude and adjusted logistics regression models were built. P-values < 0.05 were considered statistically significant. Comorbidities were observed in 55.5% of patients (389/701; 95%CI: 51.8–59.1). Wasting was the most common comorbidity (30.2%; 212/701) and pneumonia was the least common (1.7%; 12/701). Children born with a low birth weight were 2.420 times more likely to have comorbidities, adjusted odds ratio: 2.420 (95% CI: 1.339–4374). The median (interquartile range) duration of hospitalization was significantly higher in children with comorbidities than without comorbidities, 5 days (3–7) and 4 days (3–6), respectively (p-value < 0.001). One in every two children with diarrhea in Mozambique has an additional health impairment, and this increases the length of their hospital stay.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent12
dc.format.extent800938
dc.identifier.doi10.1371/journal.pone.0292093
dc.identifier.issn1932-6203
dc.identifier.otherPURE: 83042020
dc.identifier.otherPURE UUID: d9166dbb-d9a3-4924-b996-46664631b419
dc.identifier.otherScopus: 85172711052
dc.identifier.otherPubMed: 37751426
dc.identifier.otherPubMedCentral: PMC10522033
dc.identifier.otherWOS: WOS:001079916200011
dc.identifier.urihttp://hdl.handle.net/10362/164751
dc.identifier.urlhttps://www.scopus.com/pages/publications/85172711052
dc.language.isoeng
dc.peerreviewedyes
dc.subjectRA Public aspects of medicine
dc.subjectGeneral
dc.subjectInfectious Diseases
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectPediatrics, Perinatology, and Child Health
dc.subjectSDG 3 - Good Health and Well-being
dc.subjectSDG 10 - Reduced Inequalities
dc.titleExamining comorbidities in children with diarrhea across four provinces of Mozambiqueen
dc.title.subtitleA cross-sectional study (2015 to 2019)en
dc.typejournal article
degois.publication.issue9 September
degois.publication.titlePLoS ONE
degois.publication.volume18
dspace.entity.typePublication
rcaap.rightsopenAccess

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